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Zeitschrift für Gerontologie und Geriatrie
Erschienen in:

01.04.2017 | Original Contribution

Erythrocyte rheological properties but not whole blood and plasma viscosity are associated with severity of hypertension in older people

verfasst von: Guo-xiang Fu, Min Ji, Li-zhi Han, Chan-chan Xu, Feng-feng Pan, Ting-jun Hu, Yuan Zhong

Erschienen in: Zeitschrift für Gerontologie und Geriatrie | Ausgabe 3/2017

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Abstract

Objective

This study was carried out to determine whether changes in hemorheological parameters parallel the severity of essential hypertension.

Methods

A total of 198 older hypertensive patients were recruited and classified into 3 stages of hypertension according to the grading standard of hypertension. The whole blood viscosity (WBV) at various shear rates, plasma viscosity and erythrocyte rheology (including erythrocyte rigidity index, erythrocyte aggregation index and erythrocyte deformation index) were examined.

Results

Erythrocyte rheology paralleled the severity of essential hypertension and was significantly correlated to the average 24 h systolic blood pressure and diastolic blood pressure. Logistic analysis revealed that erythrocyte rigidity and the erythrocyte aggregation index were positively correlated with the severity of hypertension, while the erythrocyte deformation index was negatively correlated. No association was found between WBV, plasma viscosity and the severity of hypertension.

Conclusion

The rheological properties of erythrocyte viscosity were correlated with the severity of hypertension in older people but the WBV and plasma viscosity were not.
Vorheriger Artikel Mobile geriatrische Rehabilitation in der gesetzlichen Krankenversicherung: Konzeptionelle Ausrichtung und Ergebnisse der bundesweiten Basisdokumentation (Teil 1)
Nächster Artikel „Lesbian, gay & grey“
Literatur
1.
2.
Chien S (1977) Blood rheology in hypertension and cardiovascular disease. Cardiovasc Med 2:356–360
3.
Yapislar H, Taskin E (2014) L‑carnosine alters some hemorheologic and lipid peroxidation parameters in nephrectomized rats. Med Sci Monit 11(20):399–405
4.
Bhavsar J, Rosenson RS (2010) Adenosine transport, erythrocyte deformability and microvascular dysfunction: an unrecognized potential role for dipyridamole therapy. Clin Hemorheol Microcirc 44:193–205PubMed
5.
Jae SY, Kurl S, Laukkanen JA et al (2014) Higher blood hematocrit predicts hypertension in men. J Hypertens 32:245–250CrossRefPubMed
6.
Letcher RL, Chien S, Pickering TG, Sealey JE, Laragh JH (1981) Direct relationship between blood pressure and blood viscosity in normal and hypertensive subjects. Role of fibrinogen and concentration. Am J Med 70:1195–1202CrossRefPubMed
7.
Fowkes FG, Lowe GD, Rumley A, Lennie SE, Smith FB, Donnan PT (1993) The relationship between blood viscosity and blood pressure in a random sample of the population aged 55 to 74 years. Eur Heart J 14:597–601CrossRefPubMed
8.
Carallo C, Irace C, De Franceschi MS et al (2011) The effect of aging on blood plasma viscosity. An 11.6 years follow-up study. Clin Hemorheol Microcirc 47:67–74PubMed
9.
Pickering TG, Hall JE, Appel LJ et al (2005) Recommendations for blood pressure measurement in humans and experimental animals: Part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Hypertension 45:142–161CrossRefPubMed
10.
Baskurt OK, Boynard M, Cokelet GC et al (2009) New guidelines for hemorheological laboratory techniques. Clin Hemorheol Microcirc 42:75–97PubMed
11.
Jones JG, Adams RA, Evans SA (1994) Bulk filtration through micropore membranes for analysing blood cell rheology in clinical research. Clin Hemorheol 14:149–169
12.
13.
International Committee for Standardization in Haematology (1986) Expert panel on blood rheology. Clin Hemorheol 6:439–452
14.
Bertoluzzo SM, Bollini A, Rasia M, Raynal A (1999) Kinetic model for erythrocyte aggregation. Blood Cells Mol Dis 25:338–348CrossRef
15.
Tomita M, Gotoh F, Tanahashi N, Turcani P (1986) Whole blood red blood cell aggregometer for human and feline blood. Am J Physiol 251:H1205–H1210PubMed
16.
Brooks DE, Greig RG, Janzen J (1980) Mechanisms of erythrocyte aggregation. In: Erythrocyte mechanics and blood flow. Alan R. Liss Inc., New York, pp 119–140
17.
White WB, Berson AS, Robbins C et al (1993) National standard for measurement of resting and ambulatory blood pressures with automated sphygmomanometers. Hypertension 21:504–509CrossRefPubMed
18.
Hinshaw LB (1996) Sepsis/septic shock: participation of the microcirculation: an abbreviated review. Crit Care Med 2:1072–1078CrossRef
19.
Ajmani RS (1997) Hypertension and hemorheology. Clin Hemorheol Microcirc 17:397–420PubMed
20.
Shabanov VA, Terekhina EV, Kostrov VA (2001) Changes in blood rheological properties in patients with hypertension. Ter Arkh 73:70–73PubMed
21.
Janvier F, Zhu JX, Armstrong J, Meiselman HJ, Cloutier G (2013) Effects of amphiphilic star-shaped poly (ethylene glycol) polymers with a cholic acid core on human red blood cellaggregation. J Mech Behav Biomed Mater 18:100–107CrossRefPubMed
22.
Chabanel A, Zuccarelli F, Samama MM (1995) Red cell aggregability increases with the severity of venous insufficiency. Int Angiol 14:69–73PubMed
23.
24.
Michalska-Małecka K, Słowińska-Łożyńska L (2012) Aggregation and deformability of erythrocytes in primary open-angle glaucoma (POAG); the assessment of arterialhypertension. Clin Hemorheol Microcirc 51:277–285PubMed
25.
Salazar VBY, Martini J, Chávez NA et al (2010) Intaglietta M. Cardiovascular benefits in moderate increases of blood and plasma viscosity surpass those associated with lowering viscosity: experimental and clinical evidence. Clin Hemorheol Microcirc 44:75–85
26.
Salazar Vázquez BY, Salazar Vázquez MA, Intaglietta M, De Faire U, Fagrell B, Cabrales P (2009) Hematocrit and mean arterial blood pressure in pre- and postmenopause women. Vasc Health Risk Manag 5:483–488
27.
Alkuraishy HM, Al-Gareeb AI, Albuhadilly AK (2014) Vinpocetine and pyritinol: a new model for blood rheological modulation in cerebrovascular disorders – a randomized controlled clinical study. Biomed Res Int 2014:324–307CrossRef
28.
Baskurt OK, Meiselman HJ (1997) Cellular determinants of low-shear blood viscosity. Biorheology 34:235–247CrossRefPubMed
29.
Takiwaki M, Tomoda F, Koike T et al (2014) Increased levels of small dense low-density lipoprotein cholesterol associated with hemorheological abnormalities in untreated, early-stage essential hypertensives. Hypertens Res 37:1008–1013CrossRefPubMed
30.
Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P, Rumley A, Lowe GDO (2001) Fibrin D‑dimer and coronary heart disease: prospective study and meta-analysis. Circulation 103:2323–2327CrossRefPubMed
31.
Lowe GDO, Rumley A (1999) Use of fibrinogen and fibrin-dimer in prediction of arterial thrombotic events. Thromb Haemost 82:667–672PubMed
32.
Kario K, Matsuo T, Kobayashi H, Yamamoto K, Shimada K (1997) Earthquake-induced potentiation of acute risk factors in hypertensive elderly patients: possible triggering of cardiovascular events after a major earthquake. J Am Coll Cardiol 29:926–933CrossRefPubMed
33.
Soma P, Pretorius E (2015) Interplay between ultrastructural findings and atherothrombotic complications in type 2 diabetes mellitus. Cardiovasc Diabetol 31(14):96CrossRef
Metadaten
Titel
Erythrocyte rheological properties but not whole blood and plasma viscosity are associated with severity of hypertension in older people
verfasst von
Guo-xiang Fu
Min Ji
Li-zhi Han
Chan-chan Xu
Feng-feng Pan
Ting-jun Hu
Yuan Zhong
Publikationsdatum
01.04.2017
Verlag
Springer Medizin
Erschienen in
Zeitschrift für Gerontologie und Geriatrie / Ausgabe 3/2017
Print ISSN: 0948-6704
Elektronische ISSN: 1435-1269
DOI
https://doi.org/10.1007/s00391-016-1039-8

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