Background
Premenstrual Syndrome (PMS) refers to a comprehensive syndrome characterized by cyclic changes in spiritual, physical, and behavioral aspects that occur during the luteal phase of the menstrual cycle (specifically 7–14 days before menstruation) in women of reproductive age [
1]. Anxiety, lack of concentration, abdominal and breast pain, and irritability are the main symptoms, which are alleviated after menstruation [
1]. Globally, approximately 47.8% of women of childbearing age suffer from PMS [
2], a condition that can adversely impact their work performance to varying degrees [
3]. Research has highlighted that PMS is more prevalent among working women, and the nature of one’s occupation is intimately tied to both the occurrence and severity of PMS symptoms [
4]. Notably, in China, an overwhelming 96.6% of professional nursing personnel are women [
5], emphasizing the importance of understanding and addressing PMS in this critical workforce. As a special group of women of childbearing age, nurses are under increasing competitive pressure in society, and the potential cumulative effects of PMS on their physical and mental well-being are significant and cannot be ignored [
6].
Occupational Stress is a state of physical and mental stress that occurs when practitioners are faced with an imbalance between occupational demands and their perceptions and a mismatch between their work abilities in an occupational setting [
7]. Nurses are already one of the three groups with the highest occupational stress [
8]. Nursing staff, as the cornerstone of nursing career development, face persistent high workloads that frequently result in a sudden surge of work pressure, this sustained stress can lead to job burnout and occupational fatigue, posing a significant challenge to the progress and well-being of the nursing profession [
9]. The study has shown a connection between stress and the initiation and advancement of PMS in women [
10]. The etiology and pathogenesis of PMS are not clearly defined, and clinical practice focuses on symptomatic treatment. However, with the rise of the biopsychosocial medicine model, the leading roles of psychological, as well as sociocultural factors, in the onset, development, and transformation of PMS have gradually gained attention. It has been found that women are prone to negative emotions and avoidance attitudes when faced with negative stressful life events, which indirectly act on the route of operation of the hypothalamic-pituitary-ovarian axis, leading to disorders of hormone metabolism in the body, and subsequently inducing or exacerbating PMS [
11]. Therefore, as a group of nurses with high occupational stress, it is crucial to comprehend the status and correlation of PMS in nurses.
Sleep is the fundamental physiological requirement for human survival, and a sound sleep state effectively alleviates both physical and mental exhaustion, regulates the body’s immune system, and enhances overall physical and mental wellbeing [
12]. The quality of sleep directly influences an individual’s work performance, quality of work, and productivity [
13]. Nursing shifts are often irregular, characterized by a high prevalence of night shifts and intensified workloads, thereby rendering nurses a vulnerable group prone to poor sleep quality [
14]. Multiple factors contribute to nurses’ sleep quality, including depression, fatigue, and alterations in lifestyle. Notably, occupational stress stands out as a significant factor that cannot be overlooked [
15,
16]. Furthermore, a Korean study also underscored the significance of healthy sleep hygiene in managing dysmenorrhea and PMS. Poor subjective sleep quality, prolonged sleep latency, recurrent sleep disturbances, increased daytime dysfunction, and frequent reliance on sleeping aids were identified as components of sleep quality that exacerbate dysmenorrhea and PMS [
17].
Currently, the majority of research on PMS primarily focuses on university students [
18,
19], with relatively limited studies investigating the prevalence of PMS among nursing staff and its associated occupational factors. A study by Chen et al. in 2022 showed that the incidence of PMS in emergency nurses was 67.64%, and PMS symptoms were positively correlated with occupational stress and anxiety scores, while negatively correlated with educational level [
20]. A 2023 study by Li et al. identified several predictors of PMS in nurses, including tea or coffee consumption, trait coping styles, anxiety, depression, and perceived stress levels [
6]. Prior studies conducted by Hungarian scholars on PMS in women have demonstrated that those experiencing higher levels of perceived stress are more likely to suffer from PMS [
10]. Similarly, Turkish researchers have uncovered that sleep quality significantly influences the occurrence of PMS among medical and nursing students [
21]. Consequently, this study hypothesizes that sleep quality serves as a mediating factor between occupational stress and the onset of PMS.
In summary, this study aims to investigate the relationship between occupational stress, sleep quality and PMS among clinical nurses, and whether sleep quality serves as a mediator between occupational stress and the occurrence of PMS. It is hoped that nursing managers can take effective measures from the perspective of occupational stress and sleep quality, provide a new direction for the management of nurses in clinical work, and provide a theoretical basis for clinical nurses to carry out targeted preventive healthcare measures in the premenstrual period.
Discussions
The results of this study showed that the total occupational stress score of clinical nurses was (73.83 ± 18.18), which was moderate according to the scale rating criteria and lower than the results of the study by Wu et al. [
30]. It may be because the workplace of the subjects of this study is a small tertiary hospital, which is less intensive than top-ranking hospitals, thus resulting in a relatively low level of occupational stress. Among them, time distribution and work quantity allocation scored the highest, probably because the concept of “patient-centered” nursing has become increasingly popular, the demands on the quality of nurses’ work have become higher and more difficult, and the occupational pressure faced by nurses has also increased. It also illustrates the inadequacy of nursing human resources and the lack of adequate protection for nurses.
The total score of sleep quality was (8.30 ± 4.16), and 55.9% of the nurses had poor sleep quality, indicating that clinical nurses had prominent sleep problems, which was similar to the results of the study by Wang [
31]. The daytime dysfunction dimension has the highest score, which may be related to the “shift system” work pattern that makes nurses prone to biological rhythm and endocrine disturbance, resulting in affected sleep quality [
32]. It is suggested that nursing managers should prioritize the negative effects of sleep quality on nurses and arrange working hours reasonably considering individual characteristics.
The total score of PMS was (7.00 ± 4.73), and the prevalence of PMS among nurses in this study was 68.2% (mild: 50.4%, moderate: 16.6%, and severe: 1.2%), which was high compared to the prevalence of PMS among 18–25 year old females in Turkey (49.2%) [
33], and was close to the prevalence of PMS among female university students in China (67.0%) [
18]. In this study, nurses with PMS had more psychiatric symptoms than somatic symptoms and psychiatric symptoms were dominated by symptoms of excitability and anxiety. It suggests that the mental state of nurses should be paid attention to, and it is important to explore new management methods to reduce the mental influence of PMS in nurses. This includes providing regular mental health education and training specifically for PMS, in order to enhance nurses’ cognition and coping abilities. Additionally, implementing flexible working arrangements can help reduce the physical and mental burden on nurses. Strengthening team communication and cooperation is also crucial, so that nurses can receive support and assistance from their colleagues when facing PMS symptoms. Furthermore, the hospital should consider setting up a relaxation area, equipped with yoga mats, meditation music, and other facilities, and encourage nurses to engage in relaxation training, such as deep breathing and meditation, during breaks to alleviate tension.
This study found a positive correlation between occupational stress and sleep quality among clinical nurses, which supports the results of Yu et al. [
34]. This means that the more occupational stress felt by clinical nurses, the poorer their sleep quality. When individuals are continuously stimulated by occupational stress and fail to experience high-quality sleep over a long period, role conflict and loss of coping control can gradually develop [
35]. In China’s tense medical environment, clinical nurses, due to the specificity of their work and societal expectations, have to stand for long periods during their shifts. The alarm fatigue from various instruments and equipment, combined with the impact of the “shift system” work pattern, generates significant occupational stress and markedly affects their sleep quality. Chronic sleep deprivation among clinical nurses may lead to slower reactions, impaired thinking, and depersonalization, making them more vulnerable to nursing errors and medical malpractice [
36]. It is suggested that nursing managers should provide clinical nurses with decompression training and psychological support in time, improve and reduce the degree of physical and mental stress of nurses from multiple angles, and promote the occupational health of nurses.
Secondly, the study demonstrated a positive association between sleep quality and PMS in clinical nurses, the worse the quality of sleep, the more severe the degree of PMS. The findings align with prior studies on female medical students [
37] and Korean high school students [
17]. Good sleep can relieve PMS-related symptoms and anxiety, improve learning and work efficiency, and enhance physical health. On the contrary, Poor sleep quality can cause dysfunction of the neuroendocrine system (hypothalamic-pituitary-ovarian axis) and disruption of estrogen and progesterone secretion, increase the number of awakenings, and reduce sleep efficiency, which directly predicts the severity of PMS. It leads to their emotional instability and makes them more prone to all kinds of physical discomforts. Sleep is recognized as an important variable in PMS interventions [
38], progesterone therapy and vitamin supplementation are also commonly used clinically to reduce PMS symptoms [
39]. It is suggested that high-quality sleep management for clinical nurses should receive more attention and that nursing managers should rationalize the frequency and number of night shifts.
Furthermore, this research demonstrated a direct correlation between occupational stress and the incidence of PMS among clinical nurses. This was consistent with the findings of Sun et al. that stress is a major contributor to PMS [
40]. When Yi et al. investigated the incidence of PMS and its influencing factors in 143 female college students, they found that the severity of PMS was directly related to stress and that individual stress, depression, and dietary attitudinal problems all led to an increased likelihood of PMS [
19]. Nursing staff experience high occupational stress due to workload, high-intensity and high-risk work characteristics, complex interpersonal relationships, patient care, and other factors [
41]. This stressful environment may cause nurses to experience emotional fluctuations and trigger physical and mental tension responses. When these reactions become too strong or persistent, exceeding the individual’s ability to self-regulate, they may lead to a series of pathological signs that ultimately affect both physical and mental health, including increasing the risk of PMS.
This study showed that sleep quality mediates the relationship between occupational stress and the development of PMS in clinical nurses, with a mediation effect value of 0.173 and a mediation effect of 49.57% of the total effect. That is, occupational stress can influence the occurrence or aggravation of PMS in clinical nurses through sleep quality.
Clinical nurses, as a special category of people in their profession, face all kinds of patients every day and are under the high pressure of high work intensity and heavy workload for a long time. The overloaded workload and rigorous nature of the job inevitably affect the quality of sleep. The organism is prone to symptoms such as easy fatigue, poor concentration, memory loss, and emotional instability due to poor sleep quality [
42]. The circadian rhythm of sleep affects the regularity and function of the reproductive system and has important implications for women’s health. Therefore, poor sleep quality due to occupational stress felt by clinical nurses, indirectly increases the occurrence of PMS, both physically and psychologically, which seriously affects the efficiency of clinical nurses and increases the occurrence of nursing risk events. Nurses themselves can prevent or alleviate PMS by regulating negative emotions and routines, being physically active, and taking vitamin supplements. Nursing managers can help them release stress by carrying out targeted health education and preventive health care measures, rationalizing shift scheduling, enhancing nursing interpersonal resources, improving treatment, and paying more attention to whether nurses have sleep problems and their mental state, to reduce the incidence of PMS and thus maintain physical and mental health.
There are some limitations to this study: Firstly, this study suffers from the inherent shortcomings of cross-sectional studies such as recall bias and difficulties in inferring causal conclusions. Secondly, the questionnaire was selected using a convenience sampling method, which may have affected the representativeness of the sample. Finally, the survey object of this study was confined to a single hospital in Huaian City, Jiangsu Province, which may limit the generalizability of the findings to clinical nurses nationwide. The sampling scope thus requires further expansion. Furthermore, the study did not differentiate between job roles, such as shift workers versus full-time employees, managers versus general staff. As such, differences in work pressure and time arrangements, which can significantly impact sleep quality by, for instance, disrupting sleep-wake cycles or causing chronic stress, may not have been fully captured. Therefore, the results may not be entirely comprehensive. It is recommended that future research endeavors analyze the specific causes of differences by job position and develop targeted intervention strategies for hospital administrators to enhance nurses’ working environment, job satisfaction, and ultimately, sleep quality.
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