Needle stick injuries are common and significant occupational hazards for healthcare workers [
1]. Needle stick is a term for occupational accidents caused by healthcare workers needles or medicalusing needles, or sharp objects that come into contact with fluids [
2]. Due to the nature of their work, healthcare workers face a wide range of chemical, physical, and biological occupational hazards. They are often exposed to injuries caused by needles and sharp tools [
3,
4]. Needle stick injury statistics are estimated to be even more common than the rates reported to the Committee on Infection Control. Nurses perform the most hazardous activities because they spend more time with patients than other medical personnel [
5]. Many reports show that health workers are at risk of HBV, HCV, and HIV infections because they are exposed to blood and body fluids [
6]. Every year, a large number of healthcare workers around the world are infected in this way. Needle stick injuries are caused through the skin and usually the hands are accidental occupational exposures [
7‐
9]. Attention to the consequences of common needle stick injuries is strongly focused on the risk of infection from blood-borne pathogens [
10]. Needle stick injuries are the most common occupational hazard for nurses and other healthcare workers. These are the most common way of transmitting viruses or infections, such as HIV and hepatitis, from blood-contaminated needles and sharp objects to healthcare workers [
11]. Needle stick Injuries are defined as accidental penetrating skin injuries caused by needles. In developing countries, needle stick injuries are associated with the highest global prevalence of HIV, hepatitis B, and hepatitis C transmission [
12]. Occupational exposure exposes health service providers to various infections that threaten the health process [
13]. The rate of occupational injuries among healthcare workers due to needle sticks is 19–76% [
14]. Approximately 66.7% of nursing staff are exposed to needle and sharp tools injuries during their working hours in the hospital [
12]. An injury is an incised wound caused by the penetration of a needle or sharp tool. Each year, more than half a million healthcare workers experience a needle stick injury, increasing exposure to infectious diseases [
15]. due to improper disposal and failure to comply with standard precautions [
16]. Needle stick, as a type of occupational accident, is rooted in many causes, including a weak safety environment or non-compliance with standard precautions [
17]. Among different countries, 3.6% of infections occur in Iran [
6]. Hepatitis B is highly infectious and has the heaviest public health burden of all hepatitis viruses. More than 292 million people worldwide are chronically infected and up to 2.4 million in the United States develop silent clinical liver damage after infection. It has surpassed other major infectious diseases (such as HIV, diarrheal disease, malaria, and tuberculosis) as the leading cause of death worldwide. Prevention of transmission is essential [
18]. Hepatitis causes about 1.34 million deaths worldwide each year. 1.95% of deaths and complications caused by viral hepatitis are due to chronic hepatitis B and C. 3–5% of Iran’s population is infected with HBV. In 70% of cases, these viral hepatitis strains, highly endemic to sub-Saharan Africa, progress to chronicity, leading to liver cirrhosis and hepatocellular carcinoma, the most common cause of death among HBV and HCV patients. Both HBV and HCV are transmitted through contact with body fluids, especially blood, which are commonly encountered by health care workers through needle stick injuries [
19]. One of the confident ways to prevent infections in occupational exposures is compliance with standard precautions. They include hand hygiene, use of personal protective equipment (such as gloves, glasses, and masks), environmental control, waste management and prevention of injuries caused by sharp tools. [
20,
21]. Compliance with standard precautions is required as the primary strategy in preventing infections. All hospital staff should have adequate knowledge and skill to implement standard precautions globally [
21]. Increased awareness among health care workers and improved needle stick injury reporting systems are necessary to ensure greater protection and early use of prophylaxis after exposure. Implementing safety precautions, safe injection practices and providing engineered safety devices may further reduce the risk [
15]. Protective equipment, safety protocols, and tools modification can reduce exposure to hazards [
22]. The underreporting of needle stick injuries is still pressing concerns among nursing students [
22]. The awareness and empowerment were higher in students who received needle sticks and occupational accident preventive training. Increasing awareness and empowering nursing students through education can reduce the incidence and underreporting of needle sticks [
22]. Proper knowledge, safe injection methods, and how to handle needles are important concepts for nurses and healthcare workers [
23]. Health and occupational safety in health care workers (HCWs) and compliance with relevant standards and transmission-based precautions are also critical [
24]. Surprisingly, the knowledge of nurses and other healthcare workers about needle stick injuries was low. It is important to note that compliance with standard precautions is significantly related to the knowledge. The lower the knowledge, the poorer the compliance, leading to more needle stick incidences. Long-term educational programs are necessary to improve the knowledge of nursing students [
25]. The results of different studies showed that the educational intervention based on the health belief model can improve the students’ performance in preventing school injuries [
26]. Prevention of needle stick injuries requires situational awareness, which is obtained by using appropriate techniques. Also, the appropriate responses are to conduct risk assessment and group discussions [
27]. Choosing the appropriate educational model is the first step in the educational planning. HBM determines the relationship between health beliefs and behavior [
28]. This model has six constructs: perceived sensitivity, perceived severity, perceived benefits, perceived barriers, self-efficacy, and cues to action [
29]. Despite using personal protective equipment, the risk of self-contamination of health care workers is still high [
29]. Providing education on using safety equipment, initial handling of biohazards, and continuous monitoring the staff can improve the nurses’ compliance with standard precautions [
30]. Standard precautions are recommended safety measures for healthcare professionals to prevent healthcare-associated infections. Inadequate adherence to these measures can lead to occupational accidents [
31]. Education increases health beliefs. Health workers’ awareness regarding the risks of needle stick injuries is insufficient and requires regular training. This ongoing education improves safety cues in health care workers, which subsequently increases the overall level of compliance with standard precautions among nurses. By highlighting interests and removing barriers by proposing workable solutions appropriate knowledge can improve perceived benefits and cues to action, so better performance can be expected [
6]. The results showed that HBM constructs are important predictors for compliance with standard precautions among Iranian nurses [
32,
33]. According to the health belief model, to adopt preventive actions, people must first feel the risk of the problem (perceived sensitivity), then understand the severity of the various physical and psychological effects of the problem (perceived severity), and take preventive action in case of a positive evaluation of the benefits and the absence of serious barriers. This model has been developed on the basis that it causes people to perceive a health threat, increases their perception of sensitivity and severity of the threat; improves their understanding of benefits of preventive behavior, its perceived barriers and promotes cues to action towards performing health behavior.