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Zeitschrift für Gerontologie und Geriatrie

27.01.2025 | Themenschwerpunkt

Diagnosis of chronic obstructive pulmonary disease (COPD) in older patients

Consensus statement of the Working Group on Pneumology in Older Patients

verfasst von: C. Stenmanns, N. Netzer, C. Münks-Lederer, A. Schlesinger, S. Stieglitz, Prof. Dr. H. Frohnhofen

Erschienen in: Zeitschrift für Gerontologie und Geriatrie

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Abstract

Chronic obstructive pulmonary disease (COPD) is a frequent disease from which approximately 8% of individuals aged 40 years and above suffer. The prevalence increases up to fivefold as age advances. Following an introduction including the etiology, measurement, characteristic features and classification of COPD, this article presents the consensus recommendations of the German Working Group on Pneumology in Older Patients. These include statements on the screening for frailty, dysphagia, malnutrition and cognitive impairment. The results are summarized with the final conclusion that adequate treatment of COPD can also slow the progression of cognitive decline and could potentially prevent or delay the onset of dementia.

Al Wachami N, Guennouni M, Iderdar Y et al (2024) Estimating the global prevalence of chronic obstructive pulmonary disease (COPD): a systematic review and meta-analysis. BMC Public Health 24:297. https://doi.org/10.1186/s12889-024-17686-9CrossRefPubMed

Albarrati AM, Gale NS, Enright S et al (2016) A simple and rapid test of physical performance inchronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 11:1785–1791. https://doi.org/10.2147/COPD.S106151CrossRefPubMedPubMedCentral

Andrianopoulos V, Gloeckl R, Boensch M et al (2019) Improvements in functional and cognitive status following short-term pulmonary rehabilitation in COPD lung transplant recipients: a pilot study. ERJ Open Res. https://doi.org/10.1183/23120541.00060-2019CrossRefPubMedPubMedCentral

Andrianopoulos V, Gloeckl R, Vogiatzis I et al (2017) Cognitive impairment in COPD: should cognitive evaluation be part of respiratory assessment? Breathe 13:e1–e9. https://doi.org/10.1183/20734735.001417CrossRefPubMedPubMedCentral

Angulo J, El Assar M, Rodriguez-Manas L (2016) Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults. Mol Aspects Med 50:1–32. https://doi.org/10.1016/j.mam.2016.06.001CrossRefPubMed

Bellia V, Pistelli R, Catalano F et al (2000) Quality control of spirometry in the elderly. The SA.R.A. study. SAlute respiration nell’anziano = respiratory health in the elderly. Am J Respir Crit Care Med 161:1094–1100. https://doi.org/10.1164/ajrccm.161.4.9810093CrossRefPubMed

Bernabeu-Mora R, García-Guillamón G, Valera-Novella E et al (2017) Frailty is a predictive factor of readmission within 90 days of hospitalization for acute exacerbations of chronic obstructive pulmonary disease: a longitudinal study. Ther Adv Respir Dis 11:383–392. https://doi.org/10.1177/1753465817726314CrossRefPubMedPubMedCentral

Celli B, Fabbri L, Criner G et al (2022) Definition and nomenclature of chronic obstructive pulmonary disease: time for its revision. Am J Respir Crit Care Med 206:1317–1325. https://doi.org/10.1164/rccm.202204-0671PPCrossRefPubMedPubMedCentral

Cvejic L, Bardin PG (2018) Swallow and aspiration in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 198:1122–1129. https://doi.org/10.1164/rccm.201804-0704PPCrossRefPubMed

10.

Cvejic L, Harding R, Churchward T et al (2011) Laryngeal penetration and aspiration in individuals with stable COPD. Respirology 16:269–275. https://doi.org/10.1111/j.1440-1843.2010.01875.xCrossRefPubMed

11.

Dent E, Martin FC, Bergman H et al (2019) Management of frailty: opportunities, challenges, and future directions. Lancet 394:1376–1386. https://doi.org/10.1016/S0140-6736(19)31785-4CrossRefPubMed

12.

Eastus CC, Baez DE, Buckley ML et al (2022) The role of structured exercise interventions on cognitive function in older individuals with stable Chronic Obstructive Pulmonary Disease: A scoping review. Front Rehabil Sci 3:987356. https://doi.org/10.3389/fresc.2022.987356CrossRefPubMedPubMedCentral

13.

Etgen T, Sander D, Bickel H et al (2011) Mild cognitive impairment and dementia: the importance of modifiable risk factors. Dtsch Ärztebl Int 108:743–750. https://doi.org/10.3238/arztebl.2011.0743CrossRefPubMedPubMedCentral

14.

Fried LP, Tangen CM, Walston J et al (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56:M146–M156. https://doi.org/10.1093/gerona/56.3.m146CrossRefPubMed

15.

Frohnhofen H, Schlitzer J, Stieglitz S (2022) Lungenfunktionsprüfung im höheren Lebensalter. Z Gerontol Geriat 55:603–612. https://doi.org/10.1007/s00391-022-02070-2CrossRef

16.

Gale NS, Albarrati AM, Munnery MM et al (2018) Frailty: a global measure of the multisystem impact of COPD. Chron Respir Dis 15:347–355. https://doi.org/10.1177/1479972317752763CrossRefPubMedPubMedCentral

17.

Gephine S, Saey D, Grosbois J‑M et al (2022) Home-based pulmonary rehabilitation is effective in frail COPD patients with chronic respiratory failure. Chronic Obstr Pulm Dis 9:15–25. https://doi.org/10.15326/jcopdf.2021.0250CrossRefPubMed

18.

Gu C, Ma M, Xu J et al (2022) Association between pulmonary ventilatory function and mild cognitive impairment: a population-based study in rural China. Front Public Health 10:1038576. https://doi.org/10.3389/fpubh.2022.1038576CrossRefPubMedPubMedCentral

19.

Higbee DH, Granell R, Hemani G et al (2021) Lung function, COPD and cognitive function: a multivariable and two sample mendelian randomization study. BMC Pulm Med 21:246. https://doi.org/10.1186/s12890-021-01611-6CrossRefPubMedPubMedCentral

20.

Holmes SJ, Allen SC, Roberts HC (2017) Relationship between lung function and grip strength in older hospitalized patients: a pilot study. Int J Chron Obstruct Pulmon Dis 12:1207–1212. https://doi.org/10.2147/COPD.S120721CrossRefPubMedPubMedCentral

21.

Hong Y, Deng M, Hu W et al (2022) Weak cough is associated with increased mortality in COPD patients with scheduled extubation: a two-year follow-up study. Respir Res 23:166. https://doi.org/10.1186/s12931-022-02084-9CrossRefPubMedPubMedCentral

22.

Hopkinson NS, Molyneux A, Pink J et al (2019) Chronic obstructive pulmonary disease: diagnosis and management: summary of updated NICE guidance. BMJ 366:l4486. https://doi.org/10.1136/bmj.l4486CrossRefPubMed

23.

Lamprecht B, Soriano JB, Studnicka M et al (2015) Determinants of underdiagnosis of COPD in national and international surveys. Chest 148:971–985. https://doi.org/10.1378/chest.14-2535CrossRefPubMed

24.

Li W, Gao M, Liu J et al (2022) The prevalence of oropharyngeal dysphagia in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. Expert Rev Respir Med 16:567–574. https://doi.org/10.1080/17476348.2022.2086123CrossRefPubMed

25.

Lifshitz R, Bachner YG, Nimrod G (2023) Later life as a daring experience: factors associated with older adults’ risk perception. J Gerontol Soc Work 66:793–810. https://doi.org/10.1080/01634372.2023.2177920CrossRefPubMed

26.

Lütke A (ed) (2022) Arztcard – nationale versorgungsLeitlinie COPD – diagnostik und therapie. Biermann Verlag GmbH, Köln

27.

Marengoni A, Vetrano DL, Manes-Gravina E et al (2018) The relationship between COPD and frailty: a systematic review and meta-analysis of observational studies. Chest 154:21–40. https://doi.org/10.1016/j.chest.2018.02.014CrossRefPubMed

28.

Martin-Harris B, McFarland D, Hill EG et al (2015) Respiratory-swallow training in patients with head and neck cancer. Arch Phys Med Rehabil 96:885–893. https://doi.org/10.1016/j.apmr.2014.11.022CrossRefPubMed

29.

McDonald VM, Osadnik CR, Gibson PG (2019) Treatable traits in acute exacerbations of chronic airway diseases. Chron Respir Dis 16:1479973119867954. https://doi.org/10.1177/1479973119867954CrossRefPubMedPubMedCentral

30.

Pikus L, Levine MS, Yang Y‑X et al (2003) Videofluoroscopic studies of swallowing dysfunction and the relative risk of pneumonia. Ajr Am J Roentgenol 180:1613–1616. https://doi.org/10.2214/ajr.180.6.1801613CrossRefPubMed

31.

Rockwood K, Mitnitski A (2007) Frailty in relation to the accumulation of deficits. The journals of gerontology. J Gerontol A Biol Sci Med Sci 62:722–727. https://doi.org/10.1093/gerona/62.7.722CrossRefPubMed

32.

Rockwood K, Song X, MacKnight C et al (2005) A global clinical measure of fitness and frailty in elderly people. CMAJ 173:489–495. https://doi.org/10.1503/cmaj.050051CrossRefPubMedPubMedCentral

33.

Russ TC, Kivimäki M, Batty GD (2020) Respiratory disease and lower pulmonary function as risk factors for dementia: a systematic review with meta-analysis. Chest 157:1538–1558. https://doi.org/10.1016/j.chest.2019.12.012CrossRefPubMed

34.

Schlitzer J, Haubaum S, Frohnhofen H (2014) Treatment of chronic obstructive pulmonary disease in hospitalized geriatric patients. Z Gerontol Geriat 47:288–292. https://doi.org/10.1007/s00391-014-0645-6CrossRef

35.

Siraj RA, McKeever TM, Gibson JE et al (2021) Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): a large UK population-based study. Respir Med 177:106288. https://doi.org/10.1016/j.rmed.2020.106288CrossRefPubMed

36.

Sun X, Liu W, Gao Y et al (2023) Comparative effectiveness of non-pharmacological interventions for frailty: a systematic review and network meta-analysis. Age Ageing. https://doi.org/10.1093/ageing/afad004CrossRefPubMedPubMedCentral

37.

Tang LYW, Coxson HO, Lam S et al (2020) Towards large-scale case-finding: training and validation of residual networks for detection of chronic obstructive pulmonary disease using low-dose CT. Lancet Digit Health 2:e259–e267. https://doi.org/10.1016/S2589-7500(20)30064-9CrossRefPubMed

38.

Tasha T, Desai A, Bajgain A et al (2023) A literature review on the coexisting chronic obstructive pulmonary disease and heart failure. Cureus 15:e47895. https://doi.org/10.7759/cureus.47895CrossRefPubMedPubMedCentral

39.

Thiem U, Jäger M, Stege H et al (2023) Diagnostic accuracy of the ‘dysphagia screening tool for geriatric patients’ (DSTG) compared to flexible endoscopic evaluation of swallowing (FEES) for assessing dysphagia in hospitalized geriatric patients—a diagnostic study. BMC Geriatr 23:856. https://doi.org/10.1186/s12877-023-04516-7CrossRefPubMedPubMedCentral

40.

van Moorsel CHM (2018) Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. Curr Opin Pulm Med 24:309–317. https://doi.org/10.1097/MCP.0000000000000476CrossRefPubMedPubMedCentral

41.

Venkatesan P (2024) GOLD COPD report: 2024 update. Lancet Respir Med 12:15–16. https://doi.org/10.1016/S2213-2600(23)00461-7CrossRefPubMed

42.

Walsh B, Fogg C, Harris S et al (2023) Frailty transitions and prevalence in an ageing population: longitudinal analysis of primary care data from an open cohort of adults aged 50 and over in england, 2006–2017. Age Ageing. https://doi.org/10.1093/ageing/afad058CrossRefPubMedPubMedCentral

43.

Wang L, Zhang X, Liu X (2023) Prevalence and clinical impact of frailty in COPD: a systematic review and meta-analysis. BMC Pulm Med 23:164. https://doi.org/10.1186/s12890-023-02454-zCrossRefPubMedPubMedCentral

44.

Zhou L, Yang H, Zhang Y et al (2022) Association of impaired lung function with dementia, and brain magnetic resonance imaging indices: a large population-based longitudinal study. Age Ageing. https://doi.org/10.1093/ageing/afac269CrossRefPubMedPubMedCentral

Titel: Diagnosis of chronic obstructive pulmonary disease (COPD) in older patients
Consensus statement of the Working Group on Pneumology in Older Patients
verfasst von: C. Stenmanns
N. Netzer
C. Münks-Lederer
A. Schlesinger
S. Stieglitz
Prof. Dr. H. Frohnhofen
Publikationsdatum: 27.01.2025
Verlag: Springer Medizin
Erschienen in: Zeitschrift für Gerontologie und Geriatrie
Print ISSN: 0948-6704
Elektronische ISSN: 1435-1269
DOI: https://doi.org/10.1007/s00391-025-02409-5

Springerpflege

Abstract

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